Comparative evaluation demonstrates rapid detection of Acinetobacter baumannii outbreaks using MALDI-TOF mass spectrometry, indicating potential for real-time surveillance ahead of DNA typing.
Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been evaluated for the identification of multidrug-resistant Acinetobacter baumannii nosocomial outbreaks in comparison with the repetitive sequence-based PCR DiversiLab system. The results suggest that MALDI-TOF MS can be used for real-time detection of Acinetobacter outbreaks before results from DNA-based systems are available.
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Mencacci et al. (2012) studied this question.
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