Answers are grounded in this paper and cite their sources.
An enantioselective route for the synthesis of oxatetracyclic core of platensimycin is reported for the first time using a 5-exo-trig cyclization followed by intramolecular etherification as key reactions. The requisite dienynone for the radical cyclization is synthesized in eight steps from the Wieland-Miescher ketone employing a Claisen rearrangement.
No takes yet. Share an insight, caveat, or question.
Kaliappan et al. (2007) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: