Key result
Chronic diseases were associated with significantly lower overall health-related quality of life scores compared to healthy individuals (p < 0.001), demonstrating the sensitivity of the Health-SigQOLM scale.
Why the study?
The study aimed to assess health-related quality of life among healthy and non-healthy participants with varying chronic diseases using the Health-Significant Quality of Life Measure.
Cross-Sectional (n=452)
Yes
p-value: p=<0.001
The Health-SigQOLM is a valid and sensitive tool for measuring generic and dynamic health-related quality of life, effectively distinguishing between healthy individuals and those with various chronic diseases.
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Supports Health-SigQOLM sensitivity for research use; leaves open routine clinical adoption pending longitudinal validation.
Bujang et al. (2025) conducted a cross-sectional in Chronic diseases (end-stage renal disease, cancer, depressive disorder, coronary heart disease) (n=452). Chronic disease vs. Healthy individuals was evaluated on Mean overall Health-Related Quality of Life (HRQOL) score (p=<0.001). Chronic diseases were associated with significantly lower overall health-related quality of life scores compared to healthy individuals (p < 0.001), demonstrating the sensitivity of the Health-SigQOLM scale.
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