Key result
Self-reported pain relief from preoperative intra-articular corticosteroid injection showed a positive but weak correlation with postoperative pain relief after periacetabular osteotomy (r=0.278, P=0.016).
Why the study?
Determining which patients with acetabular dysplasia will benefit most from periacetabular osteotomy (PAO) can be challenging, and the relationship between preoperative corticosteroid injection pain relief and postoperative relief after PAO is unclear.
Does self-reported pain relief from preoperative intra-articular corticosteroid injection predict postoperative pain relief after periacetabular osteotomy?
Cohort (n=76)
No
Does self-reported pain relief from preoperative intra-articular corticosteroid injection predict postoperative pain relief after periacetabular osteotomy?
Preoperative intra-articular corticosteroid injection response has a weak positive correlation with postoperative pain relief after periacetabular osteotomy, but its negative predictive value remains low.
Answers are grounded in this paper and cite their sources.
Preoperative injection response has limited predictive value for PAO outcomes; leaves open the need for stronger prognostic tools in hip preservation.
Determining which patients with acetabular dysplasia will benefit most from periacetabular osteotomy (PAO) can be challenging. Intra-articular corticosteroid injection (CSI) is often used for therapeutic and diagnostic purposes in various hip pathologies. This study aims to assess the relationship between self-reported preoperative CSI pain relief and postoperative pain relief after PAO. The case log of a single hip-preservation surgeon was queried from 2013 onward for patients who underwent PAO with preoperative intra-articular CSI. Patients were asked, ‘overall, what percent improved are your symptoms from 0-100%?’ following preoperative CSI and again at each postoperative visit. A successful postoperative pain outcome was defined as pain relief ≥75% compared to preoperative symptoms at the approximate 6 month postoperative visit. A total of 76 hips met inclusion criteria. Average self-reported relief from preoperative intra-articular CSI was 70 ± 35%. Mean postoperative pain relief was 88 ± 18%. Analysis showed a positive but weak correlation between preoperative CSI response and postoperative relief (0.278, P = .016). Receiver operator characteristic curve analysis found CSI pain relief ≥60% to be the optimal threshold for predicting a successful postoperative pain outcome. Positive predictive value remained high and negative predictive value (NPV) remained low over a range of CSI relief thresholds. Most patients had significant pain relief following PAO, with only 10 patients failing to achieve at least 75% improvement. As a result, the NPV associated with any CSI pain relief threshold remained low. As our patients generally experienced significant postoperative pain relief regardless of preoperative CSI response, further work is warranted to identify those less likely to benefit from surgery.
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Hall et al. (2025) conducted a cohort in Acetabular dysplasia (n=76). Preoperative intra-articular corticosteroid injection (CSI) pain relief was evaluated on Postoperative pain relief after PAO (successful outcome defined as pain relief ≥75% compared to preoperative symptoms at ~6 months) (correlation 0.278, p=0.016). Self-reported pain relief from preoperative intra-articular corticosteroid injection showed a positive but weak correlation with postoperative pain relief after periacetabular osteotomy (r=0.278, P=0.016).
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