Colorimetric Enantiorecognition of Oligopeptide and Logic Gate Construction Based on DNA Aptamer–Ligand–Gold Nanoparticle Interactions

At the gate: Colorimetric enantiorecognition of one oligopeptide was realized by virtue of a D-enantiomer specific DNA aptamer as chiral selector and unmodified gold nanoparticles as indicator. Oligopeptide enantiomers as inputs were introduced into colorimetric logic gates, which have the potential for enantiorecognition of oligopeptides (see figure). This system may lead to a better understanding of chiral recognition for information processing in natural systems.