In nodular scabies the mites often disappear particularly after topical treatment that disintegrates them, thus not allowing the detection of the jetliner sign. As mite’s eggs are more resistant to treatment, is possible to identify the burrows filled with eggs, morphologically and ultrastructurally resembling ‘string of pearls’, also in nodular lesions.
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Rubegni et al. (2010) studied this question.
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