Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad

The objective of this study is to determine the resistance profile of Pseudomonas aeruginosa strains towards antibiotics in N'Djamena (CHAD). This a cross-sectional and prospective study, conducted at the Mother and Child Hospital (MCH) in N'djamena, from February to July 2016 on 550 urine samples. Uroculture and antibiotic susceptibility testing were performed according to MCH laboratory standards. Germ isolation was performed on Cetrimide agar and identification by API 20 NE gallery. The antibiogram was determined by the microgram method on Mueller-Hinton agar. A total of 15/550 (2.72%) strains of Pseudomonas aeruginosa were identified. These strains showed low resistance between 6.66% and 13.33% to Cefixime, Colistin, Gentamycin, Ciprofloxacin and Tobramycin. On the other hand, a high resistance (100%) was observed with Augmentin, Ampicillin, Cefotaxime, Ceftriaxone, Imipenem, Vancomycin, Oxacillin, Erythromycin and Tetracycline. The emergence of multiresistant bacterial strains is a major public health problem that requires adequate and adapted antibiotic therapy. Pseudomonas aeruginosa is one of the bacteria whose monitoring is more than necessary to defect the appearance of multidrug resistant strains. Given the involvement of Pseudomonas aeruginosa in several infectious pathologies, a monitoring of its profile with respect to antibiotics must be systematically carried out in all the health structures that have adequate technical platforms allowing them to perform an antibiogram.