Key result
Experimental infection with Tunisian and French Border Disease Virus strains induced mild fever and leucopaenia in lambs, demonstrating that the Tunisian isolates are pathogenic and almost similar to the French reference strain.
Population
24 four-month-old lambs from a pestivirus-free flock (3 groups of 8)
Design
Preclinical
Follow-up
21 days
Authors
Loading...
May indicate economic risk to naive flocks; leaves open field relevance and need for targeted surveillance.
Tunisian pestivirus isolates SN3G and Lot21 show similar pathogenicity to the French reference strain AV in lambs, indicating they could induce economic losses in naive flocks.
Thabti et al. (2002) studied Border Disease Virus infection (n=28). Border Disease Virus (French AV strain and Tunisian SN3G or Lot21 isolates) vs. BDV-free cell culture was evaluated on Clinical symptoms (fever, leucopaenia) and virological/immunological response. Experimental infection with Tunisian and French Border Disease Virus strains induced mild fever and leucopaenia in lambs, demonstrating that the Tunisian isolates are pathogenic and almost similar to the French reference strain.
Synapse has enriched one closely related paper. Consider it for comparative context: