Myasthenia Gravis

In order to appreciate the clinical picture of this remarkable affection, it seems appropriate to preface the description of the case with a definition of myasthenia gravis. This affection is characterized by McCarthy as "a disease with fatigue symptoms referable to the muscular system due to an exhausted condition of nervous enervation without definite pathology in the nervous system and with minor changes (lymphocytic infiltration) in the muscles." To Wilkes belongs the credit of first accurately describing this disease. Subsequently Erb, Oppenheim, Eisenlohr, Bernhardt, Strümpell, Campbell and Bramwell, in a series of articles and reports of cases, definitely established the clinical entity of the malady. Goldflam's contention that the disease is not immediately fatal and may be subject to marked remissions over a lengthy period is borne out by our patient, whose history dates back nearly five years. The relation of the disease to the endocrine disturbances, while not conclusive,