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PUVA lentigines do not subside after discontinuation of photochemotherapy. Cryotherapy with liquid nitrogen was done on a small area in a patient who presented with numerous PUVA lentigines. Five years after this treatment, the PUVA lentigines had not returned. Cosmetically disturbing PUVA lentigines can be treated with cryotherapy.
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Leroy et al. (1996) studied this question.
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