Background and Aims: Hepatitis E virus is a public health concern and about a third of people in the world live in endemic areas.Although HEV is believed to be transmitted by fecal-oral routes between humans in low sanitary conditions, but evidence of transmission have been reported in hemodialysis (HD) patients. Materials and Methods:The aim of present study was to determine the prevalence of anti-HEV antibody among HD patients in Gorgan, north of Iran.In this cross-sectional study, totally 300 HD patients from May to December 2014 were tested for detection of anti-HEV IgG and IgM by commercial HEV enzyme-linked immunosorbent assay (ELISA) kit.Demographic variables were collected in pre-designed questionnaires.Results: Out of 300 individuals, 148 (49.3%) were male and 152 (50.7%) were female.The overall anti-HEV IgG seroprevalence rate was 4%.Result showed significant association between anti-HEV IgG and duration of dialysis (p = 0.03), but there were no significant differences between the subjects grouped according to gender, Ethnicity, dialysis per week and age.No anti-HEV IgM were detected in patients.Conclusions: Since our finding showed statically significant relationship between duration of hemodialysis and anti-HEV.Therefore, hemodialysis maybe be considered as a risk factor in HEV transmission.However further studies are needed to confirm our data.
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Naziri et al. (2016) studied this question.
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