The authors describe two patients with squamous cell carcinoma arising in benign mixed tumor of the lacrimal gland. One tumor arose in a 77-year-old woman with an incompletely excised benign mixed tumor 25 years previously. the other squamous cell carcinoma was present in a 57-year-old man with a subtotally removed benign mixed tumor 20 years prior to discovery of malignant transformation. the fact that squamous cell carcinoma may arise in benign mixed tumors of the lacrimal gland is illustrated and the use of combined surgery and radiation therapy for palliation or cure of these tumors is discussed.
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Grossniklaus et al. (1988) studied this question.
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