Two cases of basal cell carcinoma (BCC) occurring in association with long-standing dermatofibroma are reported. These lesions were asymptomatic, but both were characterized clinically by central ulceration. Histopathology of both cases revealed a BCC overlying a typical dermatofibroma. The association of these two tumours has rarely been reported and is controversial. It is disputed whether the changes of BCC overlying dermatofibromata are reactive or neoplastic.
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McKenna et al. (2009) studied this question.