Key result
Quantitative T1 and T2 mapping on cardiac MRI successfully diagnosed acute global myocarditis by demonstrating diffuse myocardial edema and expanded extracellular volume.
Why the study?
Does cardiac MRI with quantitative T1 and T2 mapping enable the diagnosis of acute global myocarditis?
Case Report (n=1)
Does cardiac MRI with quantitative T1 and T2 mapping enable the diagnosis of acute global myocarditis?
Quantitative T1 and T2 mapping on cardiac MRI can facilitate the diagnosis of acute global myocarditis by objectively detecting diffuse myocardial edema and extracellular volume expansion.
May aid diagnosis of acute global myocarditis when edema is diffuse; leaves open prospective validation before broader adoption.
The diagnosis of myocarditis can be challenging given that symptoms, clinical exam findings, electrocardiogram results, biomarkers, and echocardiogram results are often non-specific. Endocardial biopsy is an established method for diagnosing myocarditis, but carries the risk of complications and false negative results. Cardiac magnetic resonance imaging (MRI) has become the primary non-invasive imaging tool in patients with suspected myocarditis. Myocarditis can be diagnosed by using three tissue markers including edema, hyperemia/capillary leak, and necrosis/fibrosis. The interpretation of cardiac MR findings can be confusing, especially when the myocardium is diffusely involved. Using T1 and T2 maps, the diagnosis of myocarditis can be made even in cases of global myocarditis with the help of quantitative analysis. We herein describe a case of acute global myocarditis which was diagnosed by using quantitative T1 and T2 mapping.
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Park et al. (2013) conducted a case report in Acute global myocarditis (n=1). Cardiac MRI with quantitative T1 and T2 mapping was evaluated on Diagnosis of acute global myocarditis using T1 and T2 values and extracellular volume fraction. Quantitative T1 and T2 mapping on cardiac MRI successfully diagnosed acute global myocarditis by demonstrating diffuse myocardial edema and expanded extracellular volume.
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