The amounts by which various weights distended isolated segments from the distal colons of guinea-pigs were measured. 2. Tetrodotoxin substantially reduced the distensibility of the intestine, but bretylium, guanethidine, hyoscine and methysergide had no significant effect. 3. It is concluded that a local reflex involving enteric inhibitory nerves causes an accomodation of the intestine to stretch.
No takes yet. Share an insight, caveat, or question.
Furness et al. (1977) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: