Thrombopenic Purpura Due to Sulfathiazole

Thrombopenic purpura has been observed and described as a manifestation of drug toxicity during the administration of sulfanilamide1and of sulfapyridine.2It has yet not been reported with the use of sulfathiazole. The following case is one in which this complication occurred. REPORT OF CASE History.— A carpenter aged 37 was admitted to the Jewish Hospital Sept. 11, 1941. He had experienced left renal colic seventeen years before and a calculus was removed from the urinary bladder by cystoscopy. Three years later a similar episode occurred. The patient then experienced good health until one year before admission, at which time he again had left renal colic. A nephrostomy was performed at another hospital but the patient did not know whether a calculus was removed. The wound healed and the patient was comfortable for the next three months. For nine months prior to admission he had frequent attacks