The range of cyclopentanoid natural products that exhibit antibiotic activity is expanded by the isolation of the crinipellins, for example, crinipellin A 1a and its O-acetyl derivative 1b. These diterpenoids, which contain an α-methylene ketone group, are produced by cultures of the fungus Crinipellis stipitaria.
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Anke et al. (1985) studied this question.
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