Answers are grounded in this paper and cite their sources.
Cell-free DNA (cfDNA) is a unique biospecimen that contains multiple sources of DNA, including tumor, germline, fetal, and others. Clonal hematopoiesis, a process that leads to expansion of mutations in peripheral blood cells, is an additional source of DNA that adds a layer of complexity when interpreting results. Clin Cancer Res; 24(18); 4352–4.
No takes yet. Share an insight, caveat, or question.
Bauml et al. (2018) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: