Key result
Endovascular hybrid repair with double graft wrapping yields 0% mortality and no major complications.
Why the study?
To describe a hybrid procedure that avoids cardiopulmonary bypass to treat patients with true ascending aortic aneurysms lacking a suitable proximal landing zone for endovascular repair.
Does the endovascular hybrid repair of true aortic aneurysms (EHTA) approach prevent mortality and aneurysm enlargement in patients with true ascending aortic aneurysms without a suitable proximal landing zone?
Cohort (n=13)
Does the endovascular hybrid repair of true aortic aneurysms (EHTA) approach prevent mortality and aneurysm enlargement in patients with true ascending aortic aneurysms without a suitable proximal landing zone?
The EHTA hybrid approach offers a feasible, beating-heart alternative for treating true ascending aortic aneurysms in high-risk patients without a suitable proximal landing zone, demonstrating early safety and efficacy.
Feasible hybrid option without bypass in select cases; leaves open durability and safety questions pending prospective trials.
Purpose: To describe a hybrid procedure that avoids cardiopulmonary bypass to treat patients with true ascending aortic aneurysms without a suitable proximal landing zone for endovascular repair. Material and Methods: Thirteen consecutive patients (mean age 75.9±6.5 years; 8 women) with true ascending aortic aneurysms were treated with the endovascular hybrid repair of true aortic aneurysms (EHTA) approach, which consists of a conventional sternotomy with double wrapping of the ascending aorta followed by staged stent-graft placement. Via sternotomy, a polypropylene mesh trimmed to downsize the aneurysm is placed around the dilated ascending aorta and sutured to the adventitia. A similarly trimmed polytetrafluoroethylene graft is placed loosely around the first wrap to avoid adhesions and secure the proximal landing zone. There is no need for cardiopulmonary bypass. A few days later, a standard thoracic stent-graft is deployed via either a transaxillary or transfemoral access; chimney or bypass grafts are used as needed to revascularize the supra-aortic vessels. Results: The ascending aortic diameter was reduced from a mean 5.7 cm (range 4.8–6.5) to 3.9 cm (range 3.2–4.3) after wrapping. The mean interval between surgery and stent-graft placement was 5 days. In this interval, 2 patients with significant reduction in the diameter of the ascending aorta elected to forego placement of a stent-graft. Of the 11 patients who underwent the full hybrid EHTA procedure, the ascending aortic stent-graft was combined with a chimney graft in the innominate artery in 4 cases. In 1 patient, a supra-aortic debranching procedure using a bifurcated Dacron graft to the innominate and left common carotid arteries was performed after wrapping with the polypropylene mesh. There was no mortality or neurological complication. A sternal wound infection required a prolonged hospital stay. At a mean follow-up of 13.8 months (range 3–24), there has been no death, type I endoleak, or sign of aneurysm enlargement on imaging. Conclusion: This technique permits complete endovascular exclusion of an ascending aortic aneurysm in a less invasive approach than standard open repair. Although this is only a small cohort of patients without long-term follow-up, it seems that this hybrid procedure is associated with low morbidity and mortality. It offers a beating-heart approach to treat true ascending aortic aneurysms in selected high-risk patients.
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Kolvenbach et al. (2019) conducted a cohort in True ascending aortic aneurysms without a suitable proximal landing zone (n=13). Endovascular hybrid repair of true aortic aneurysms (EHTA) was evaluated on Mortality, neurological complication, type I endoleak, or aneurysm enlargement. Endovascular hybrid repair of true ascending aortic aneurysms using double graft wrapping resulted in 0% mortality, no neurological complications, and no type I endoleaks at 13.8 months.
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