Key result
Third COVID-19 dose linked to severe Takotsubo and huge LV aneurysm requiring Dor's procedure.
Case Report (n=1)
No
This is the first reported case of Takotsubo syndrome complicated by a left ventricular aneurysm requiring cardiac surgery following COVID-19 vaccination.
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This isolated case of post-vaccination Takotsubo with surgical aneurysm does not alter recommendations; leaves open causality requiring larger studies.
A 72-year-old woman, recently COVID-19 vaccinated with a third dose, was referred to our center for acute chest pain and dyspnea. On admission, the electrocardiography showed a STEMI on inferior derivations and the dyskinesia of the inferior wall was found at the first transthoracic echocardiogram. The coronary angiography did not show coronary artery disease. After 1 week, a huge posterolateral left ventricular (LV) aneurysm with initial signs of rupture was found and the patient underwent a Dor's procedure to exclude the LV aneurysm. As far as we know, this is the first reported case of Takotsubo following the COVID-19 vaccination requiring cardiac surgery.
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Ceresa et al. (2022) conducted a case report in Takotsubo syndrome with left ventricular aneurysm (n=1). COVID-19 vaccination was evaluated on Development of left ventricular aneurysm requiring cardiac surgery. A 72-year-old woman developed a huge posterolateral left ventricular aneurysm requiring a Dor's procedure following a third dose of COVID-19 vaccination, representing a severe case of Takotsubo.
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