Global research status and frontiers on autophagy in hepatocellular carcinoma: a comprehensive bibliometric and visualized analysis

As we all know that Annals of Medicine and Surgery is a prestigious and top academic journal in the field of surgery, we recently read with interest some of the high-quality studies in your journal, and one of the studies titled 'Global research status and frontiers on autophagy in hepatocellular carcinoma: a comprehensive bibliometric and visualized analysis [1] ' caught our attention.This study used scientific literature search and econometric analysis to comprehensively search for studies in the field of autophagy in hepatocellular carcinoma, obtain annual publication data of these studies, summarize the countries, institutions, authors, and journals that have made significant contributions, and visualize keywords appearing in the studies, which provide a basis for observing current research hotspots and future research trends.The visualization of keywords in the research provides a basis for observing current research hotspots and future research trends, and provides an important reference for scholars who are new to the field or want to learn more about the field.As mentioned in the authors' article, autophagy in hepatocellular carcinoma is a huge public health challenge that has received a great deal of attention in recent years, suggesting the importance of this study.However, after our careful reading, we have some suggestions about certain parts of this study that we would like to discuss with the authors and our readers, and we hope that the authors will share their views and ideas.The first concern is that the author's detailed search strategy is written in a supplemental table 'TS = ((primary hepatic cancer) OR (primary liver cancer) OR (hepatocellular carcinoma) OR (malignant hepatoma) OR (primary liver carcinoma)) OR (primary hepatic carcinoma) OR (HCC)) AND ((autophagy) OR (macroautophagy) OR (microautophagy) OR (chaperone-