The utilisation of convolutional neural networks in detecting pulmonary nodules: a review

Lung cancer is one of the leading causes of cancer-related fatality in the world. Patients display few or even no signs or symptoms in the early stages, resulting in up to 75% of patients diagnosed in the later stages of the disease. Consequently, there has been a call for lung cancer screening amongst at-risk populations. The early detection of malignant pulmonary nodules in CT is one of the suggested methods proposed to diagnose early-stage lung cancer; however, the reported sensitivity of radiologists' ability to accurately detect pulmonary nodules ranges widely from 30 to 97%. 2012 saw Alex Krizhevsky present a paper titled "ImageNet Classification with Deep Convolutional Networks" in which a multilayered convolutional computational model known as a convolutional neural network (CNN) was confirmed competent in identifying and classifying 1.2 million images to a previously unseen level of accuracy. Since then, CNNs have gained attention as a potential tool in aiding radiologists' detection of pulmonary nodules in CT imaging. This review found the use of CNN is a viable strategy to increase the overall sensitivity of pulmonary nodule detection. Small, non-validated data sets, computational constraints, and incomparable studies are currently limited factors of the existing research.