Key result
CRP and clinical risk factors, but not troponin I, are linked to post-MI complications.
Why the study?
Do troponin I and C-reactive protein levels predict complications in patients after myocardial infarction?
Observational
Do troponin I and C-reactive protein levels predict complications in patients after myocardial infarction?
C-reactive protein and clinical risk factors, but not troponin I, are significant predictors of short-term complications following myocardial infarction.
CRP and clinical factors may aid post-MI risk stratification; leaves open troponin I's added value in prospective cohorts.
The aim of this study was to investigate the prognostic significance of troponin I, C-reactive protein and risk factors for the occurrence of complications after myocardial infarction. Troponin I and C-reactive protein values were analyzed in 38% of patients with complications (postinfarction angina, ventricular fibrillation, heart failure and fatal outcome) and in 62% of patients without complications. Values wererecorded on admission and between the eighth and tenth day of hospitalization. It was found that a larger number of risk factors (p = 0.00), diabetes mellitus (p = 0.02) and smoking (p = 0.01) were significantly associated with the complications. It was shown that hypertension increases the risk of developing heart failure after acute myocardial infarction (p = 0.02). It resulted with statistically non-significant difference in the observed values of troponin I between the group of patients with complications and the group without them (p = 0.22, p = 0.327). There was a statistically significant difference in the observed values of C-reactive protein in the two groups of patients (p = 0.00, p = 0.01). It can be concluded that the values of troponin I had no prognostic significance in risk stratification, while the values of C-reactive protein, individual risk factors and a large numberof risk factors hadsignificance in risk stratification after myocardial infarction.
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Hodžić et al. (2016) conducted an observational in Myocardial Infarction. Troponin I, C-reactive protein, and clinical risk factors was evaluated on Complications (postinfarction angina, ventricular fibrillation, heart failure and fatal outcome). C-reactive protein levels (p=0.00) and clinical risk factors, but not troponin I (p=0.22), were significantly associated with the development of complications after myocardial infarction.
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