Key result
Hospitalization for surgical emergencies in England compared to the US was associated with less surgical intervention and higher in-hospital mortality across all 7 conditions (mortality ORs 1.34-4.46).
Why the study?
Considerable international variation exists in the configuration, provision, and outcomes of emergency healthcare, motivating a comparison between England and the USA.
Does hospitalization in England compared to the United States affect the rate of surgical intervention and in-hospital mortality for surgical emergencies?
Observational (n=1,999,673)
Yes
Does hospitalization in England compared to the United States affect the rate of surgical intervention and in-hospital mortality for surgical emergencies?
English hospitals demonstrate a higher threshold for surgical intervention in emergencies compared to the US, which is associated with increased in-hospital mortality.
England's lower surgical intervention rates linked to higher mortality for emergencies; observational data leaves open optimal thresholds across systems.
OBJECTIVE: To examine differences between England and the USA in the rate of surgical intervention and in-hospital mortality for 7 index surgical emergencies. BACKGROUND: Considerable international variation exists in the configuration, provision, and outcomes of emergency healthcare. METHODS: Patients aged <80 years hospitalized with 1 of 7 surgical emergencies (ruptured abdominal aortic aneurysm, aortic dissection, appendicitis, perforated esophagus, peptic ulcer, small bowel or large bowel, and incarcerated or strangulated hernias) were identified from English Hospital Episode Statistics and the USA Nationwide Inpatient Sample (2006-2012) and classified by whether they received a corrective surgical intervention. The rates of surgical intervention and population mortality were compared between England and the USA after adjustment for patient demographic factors. RESULTS: From 2006 to 2012, there were 136,047 admissions in English hospitals and 1,863,626 admissions in US hospitals due to the index surgical emergencies.Proportion of patients receiving no surgical intervention, for all 7 conditions was greater in the England (OR 4.25, 1.55, 8.53, 1.92, 2.06, 2.42, 1.75) and population in-hospital mortality was greater in England (OR 1.34, 1.67, 2.22, 1.65, 2.7, 4.46, 3.22) for ruptured abdominal aortic aneurysm, aortic dissection, appendicitis, perforated esophagus, peptic ulcer, small bowel or large bowel, and incarcerated or strangulated hernias respectively.In England (where follow-up was available), lack of utilization of surgery was also associated with increased in-hospital and long-term mortality for all conditions. CONCLUSION: England and US hospitals differ in the threshold for surgical intervention, which may be associated with increases in mortality in England for these 7 general surgical emergencies.
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Markar et al. (2019) conducted an observational in Surgical emergencies (ruptured AAA, aortic dissection, appendicitis, perforated esophagus, peptic ulcer, bowel, hernias) (n=1,999,673). Healthcare system in England vs. Healthcare system in the United States was evaluated on In-hospital mortality (OR 1.34 to 4.46 (across 7 conditions)). Hospitalization for surgical emergencies in England compared to the US was associated with less surgical intervention and higher in-hospital mortality across all 7 conditions (mortality ORs 1.34-4.46).
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