Development of an Electrochemical Sensor for Catecholamine Detection via a Layer-by-layer Fabrication Method

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In this work, the Cu/MnO2/MWCNTs (MWCNTs) nanocomposite modified glass carbon electrode (GCE) was applied to the preparation of a novel sensor of catecholamine (CA) using an electrochemical strategy. Amperometry was used to investigate the electrocatalytic activity of this sensor in CA oxidation. It was found that the current response had a linear relationship with the concentration of glucose (0.65–2000 μM), and the correlation coefficient was 0.99. Meanwhile, the limit of detection (LOD) was calculated as 0.14 μM (S/N=3), and the response time was 3 s.