Key result
Review outlines mechanisms by which hydrocarbon anesthetics sensitize the myocardium to catecholamine-induced arrhythmias.
This review summarizes the mechanisms by which hydrocarbon anesthetics sensitize the heart to catecholamine-induced arrhythmias.
Answers are grounded in this paper and cite their sources.
Does not support changes in anesthetic protocols; leaves open the need for prospective validation of these mechanisms.
During the past decade, considerable progress has been made in our understanding of the mechanism underlying sensitization of the heart to the arrhythmogenic action of the catecholamines by hydrocarbon anesthetics. This review includes the following: a brief discussion on the concepts of the mechanics of induction of cardiac arrhythmia; recent studies on sensitization with special reference to the primary locus of this action and the principal mechanisms involved; and the contribution made by microelectrode studies on various types of cardiac tissue and the importance of cardiodynamic effects. In addition, atrioventricular conduction studies using bundle of His preparations are described. Drug interaction between anesthetic agents, muscle relaxants, and other drugs are discussed. Suggestions for future research and a section of summary and conclusions are included.
No takes yet. Share an insight, caveat, or question.
Alexandra Reynolds (1984) conducted a review in Cardiac arrhythmia. Hydrocarbon anesthetics was evaluated. This review discusses the mechanisms underlying myocardial sensitization to the arrhythmogenic action of catecholamines by hydrocarbon anesthetics, including microelectrode and cardiodynamic studies.
Synapse has enriched 10 related papers. Consider them for comparative context: