The survival of autografts, first set homografts and second set homografts was compared at 9°C and at 25°C in immature but metamorphosed individuals. Exposure to low temperature prolonged the survival time of second set homografts to a lesser extent than that of first set homografts. It is concluded that low temperature prolongs the survival of first set homografts by inhibiting the process of immunological activation rather than by reducing the rate of reaction between sensitized host cells and the graft.
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John D. Simnett (1965) studied this question.
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