Tumor excision significantly prolonged median survival time in patients with primary sarcoma of the pulmonary artery from 1.5 months to 10 months (p<0.01).
Does tumor excision improve survival time in patients with primary sarcoma of the pulmonary artery?
Tumor excision significantly prolongs survival in patients with primary sarcoma of the pulmonary artery, a rare condition with an otherwise extremely poor prognosis.
Absolute Event Rate: 10% vs 1.5%
p-value: p=<0.01
Primary sarcoma of the pulmonary artery is a rare tumor which must be considered in differential diagnosis of pulmonary embolism. The data of the 93 cases published up to now is evaluated synoptically after a report on a primary sarcoma of the pulmonary artery. Modern diagnostic imaging methods (pulmonary DSA, perfusion scintigraphy, echocardiography, computer tomography, nuclear magnetic resonance tomography) may corroborate the suspicion of a sarcoma of the pulmonary artery. With a median survival time of 1.5 months, the prognosis of patients with primary sarcomas of the pulmonary artery must be regarded extremely poor. After tumor excision, the median survival time of the patients could be prolonged (statistically significant; p less than 0.01) to ten months. The significance of adjuvant chemotherapy and/or radiotherapy cannot be appraised at present.
Krüger et al. (1990) conducted a review in Primary sarcoma of the pulmonary artery (n=93). Tumor excision vs. No tumor excision was evaluated on Median survival time (months) (p=<0.01). Tumor excision significantly prolonged median survival time in patients with primary sarcoma of the pulmonary artery from 1.5 months to 10 months (p<0.01).
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