Key result
Intraventricular administration of angiotensin II inhibitors did not attenuate the increase in ACTH and corticosterone secretion produced by ether stress in rats compared to vehicle.
No takes yet. Share an insight, caveat, or question.
Rat findings do not support central angiotensin II blockade for stress HPA modulation; leaves open alternative pathways or species differences.
Buckner et al. (2008) studied Ether stress. Intraventricular saralasin, enalaprilat, captopril, and L 363714 vs. Corresponding vehicles was evaluated on ACTH and corticosterone concentration in plasma. Intraventricular administration of angiotensin II inhibitors did not attenuate the increase in ACTH and corticosterone secretion produced by ether stress in rats compared to vehicle.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: