Key result
Type A behavior is linked to coronary heart disease, present in ~70% of affected men.
Why the study?
Does Type A behavior contribute to the development of coronary heart disease?
Meta-Analysis
Does Type A behavior contribute to the development of coronary heart disease?
Type A behavior, when assessed by structured interview, is associated with coronary heart disease, and recent null findings are likely attributable to methodological issues such as disease-based spectrum bias and reliance on self-report measures.
Structured Type A assessment may aid CHD risk identification; confirms association by resolving methodological biases behind recent nulls.
The findings of many studies conducted before 1978 suggest that Type A behavior (TAB) contributes to the development of coronary heart disease (CHD). In contrast, many recent studies have found no association between these variables. Through meta-analysis, several reasons for null findings are identified. First, a type of range restriction bias, disease-based spectrum (DBS) bias, produced many null findings. A study is vulnerable to DBS bias when researchers select only high-risk or diseased Ss for study. Second, self-report measures of TAB were often associated with null findings. Finally, null results were found for all studies that used fatal myocardial infarction as a disease criterion. In addition to identifying the reasons for null findings, this research suggests that TAB, as assessed by the structured interview, is associated with CHD. More Type As (70%) were found in diseased populations of middle-aged men than in healthy populations of middle-aged men (46%).
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Miller et al. (1991) conducted a meta-analysis in Coronary heart disease (CHD). Type A behavior (TAB) vs. Healthy populations / Non-Type A behavior was evaluated on Coronary heart disease (CHD). Type A behavior assessed by structured interview was associated with coronary heart disease (present in 70% of diseased vs 46% of healthy middle-aged men), despite biases causing null findings.
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