Polyvinylpyrrolidone and dextran polysaccharides have been fractionated by ultrafiltration by using newly developed membranes with sharp molecular weight cutoffs. Three different experimental techniques were employed: (a) batch ultrafiltration by using progressively more retentive membranes; (b) continuous ultrafiltration by using several similar membranes in series; (c) variable pressure ultrafiltration by using a single membrane and varying the applied pressure. Ultrafiltration is shown to be a technique of preparative fraction having the advantages of simplicity, speed, and economy.
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Richard W. Baker (1969) studied this question.
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