Key result
Atrial septal pacing enables LV-only pacing and clinical improvement in 3 HF patients with AV block.
Why the study?
AdaptivCRT provides RV-synchronized LV-only pacing when intrinsic AV conduction is normal, making LV-only pacing difficult in patients with prolonged AV conduction.
Case Report (n=3)
No
Cardiac resynchronization therapy (CRT) is effective in patients with heart failure (HF) and left ventricular (LV) dyssynchrony.1 However, not all patients respond to CRT. The AdaptivCRT (Medtronic, Minneapolis, MN) algorithm for CRT provides right ventricular (RV) synchronized LV-only pacing when intrinsic atrioventricular (AV) conduction is normal (<220 ms), or, alternatively, biventricular pacing for prolonged AV conduction. AdaptivCRT is effective in patients with normal AV conduction2; therefore, LV-only pacing in patients with prolonged AV conduction is difficult.
No takes yet. Share an insight, caveat, or question.
Murata et al. (2021) conducted a case report in Heart failure with first-degree atrioventricular block (n=3). Atrial septal pacing for left ventricular-only pacing was evaluated on Feasibility of left ventricular-only pacing and clinical improvement. Atrial septal pacing enabled successful left ventricular-only pacing in three patients with heart failure and first-degree atrioventricular block, leading to clinical improvements at 6 months.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: