Key result
CABG successfully treats severe left main CAD and STEMI in a 19-year-old lacking risk factors.
Why the study?
Premature CAD is an increasing concern in younger populations due to high morbidity, reduced quality of life, and economic burden.
Case Report (n=1)
No
This case highlights that severe premature coronary artery disease can present as STEMI in very young patients even in the absence of traditional cardiovascular risk factors.
Answers are grounded in this paper and cite their sources.
Severe premature CAD may cause STEMI in young patients without risk factors; single case leaves open prevalence and mechanisms.
Premature coronary artery disease (CAD) is defined by the early onset of significant atherosclerotic narrowing of the coronary arteries, generally occurring before age 55 in men and 60 in women. This condition is an increasing concern in cardiovascular medicine due to its impact on younger populations, resulting in greater morbidity, diminished quality of life, and a substantial economic burden. Common risk factors include dyslipidemia, hypertension, diabetes, smoking, obesity, and genetic predispositions such as familial hyperlipidemia. This case report describes a 19-year-old male with no known cardiovascular risk factors who presented with an ST-segment elevation myocardial infarction and ventricular tachycardia caused by left main coronary artery disease including the left anterior descending artery and the left circumflex artery. Despite lacking common risk factors, he underwent successful coronary artery bypass grafting with two grafts.
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Alhroub et al. (2025) conducted a case report in Premature coronary artery disease and STEMI (n=1). Coronary artery bypass grafting (CABG) was evaluated on Clinical recovery. A 19-year-old male with severe left main coronary artery disease and STEMI, lacking traditional risk factors, was successfully treated with coronary artery bypass grafting and remained symptom-free at 4 months.
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