Key result
RBCs underestimate blood flow by ~50% versus artificial tracers at high magnification.
In micro-PIV blood flow measurements, using red blood cells instead of artificial tracers at high magnifications significantly underestimates flow velocities, which has important implications for cardiovascular flow research.
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High-magnification RBC micro-PIV may underestimate flow; leaves open optimal tracer methods for cardiovascular research without practice implications.
Poelma et al. (2012) studied Blood flow measurement. Red blood cells (natural tracers) vs. Artificial tracers was evaluated on Blood flow velocity measurement accuracy. For high magnification cases, blood flow measurements using red blood cells strongly underestimate the flow by up to 50% compared to artificial tracer results, whereas for medium magnification both methods yield indistinguishable results.
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