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We present a simple, low-cost and scalable method for fabricating externally pressurized paper-based microfluidic devices. Known as microfluidic pressure in paper (µPiP), devices fabricated by this technique are capable of sustaining a pressure gradient for use in precise liquid handling and manipulation applications. In addition, the simple nature of this fabrication technique allows device designs to be scalably manufactured and deployed with minimal time, equipment and training requirements. This new platform democratizes the field of microfluidics and offers budget-friendly technology for both academic device prototyping and largescale commercial device production.
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Islam et al. (2021) studied this question.