Key result
Recurrent myocarditis following COVID-19 vaccination is attributed to underlying acute myeloid leukemia in a 25-year-old man.
Case Report (n=1)
Recurrent myocarditis after COVID-19 vaccination should prompt consideration of underlying systemic diseases, such as acute myeloid leukemia, especially when accompanied by other abnormalities like macrocytic anemia.
Recurrent myocarditis may signal occult AML; single case report leaves open any vaccination association or screening implications.
A 25-year-old man presented with chest pain and an elevated troponin level following COVID-19 vaccination. Despite initial response to nonsteroidal anti-inflammatory drugs, he developed a recurrent and relapsing course requiring multiple readmissions. Cardiac magnetic resonance imaging confirmed myocarditis. Due to progressing macrocytic anemia, he was eventually diagnosed with acute myeloid leukemia, thought to be the underlying driver of his recurrent and persistent myocarditis.
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Dobronyi et al. (2022) conducted a case report in Recurrent myocarditis and acute myeloid leukemia (n=1). COVID-19 vaccination was evaluated. A 25-year-old man developed recurrent myocarditis following COVID-19 vaccination, which was ultimately attributed to underlying acute myeloid leukemia.
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