Key result
Black race linked to ~33% lower SAVR incidence versus White race in hospitalized AS patients.
Why the study?
Racial and ethnic inequities exist in surgical aortic valve replacement for aortic stenosis, and early studies have suggested similar inequities in transcatheter aortic valve replacement.
Are there racial and ethnic inequities in the incidence of aortic stenosis diagnosis and aortic valve replacement among hospitalized patients?
Observational
Yes
Are there racial and ethnic inequities in the incidence of aortic stenosis diagnosis and aortic valve replacement among hospitalized patients?
Relative Risk: 0.67 (95% CI 0.55–0.82)
p-value: p=<0.001
Significant racial inequities exist in the diagnosis of aortic stenosis and the utilization of surgical and transcatheter aortic valve replacement, with Black patients experiencing lower rates of both compared to White patients.
Background Racial and ethnic inequities exist in surgical aortic valve replacement for aortic stenosis (AS), and early studies have suggested similar inequities in transcatheter aortic valve replacement. Methods and Results We performed a retrospective analysis of the Maryland Health Services Cost Review Commission inpatient data set from 2016 to 2018. Black patients had half the incidence of any inpatient AS diagnosis compared with White patients (incidence rate ratio [IRR], 0.50; 95% CI, 0.48–0.52; P <0.001) and Hispanic patients had one fourth the incidence compared with White patients (IRR, 0.25; 95% CI, 0.22–0.29; P <0.001). Conversely, the incidence of any inpatient mitral regurgitation diagnosis did not differ between White and Black patients (IRR, 1.00; 95% CI, 0.97–1.03; P =0.97) but was significantly lower in Hispanic compared with White patients (IRR, 0.36; 95% CI, 0.33–0.40; P <0.001). After multivariable adjustment, Black race was associated with a lower incidence of surgical aortic valve replacement (IRR, 0.67; 95% CI, 0.55–0.82 P <0.001 relative to White race) and transcatheter aortic valve replacement (IRR, 0.77; 95% CI, 0.65–0.90; P =0.002) among those with any inpatient diagnosis of AS. Hispanic patients had a similar rate of surgical aortic valve replacement and transcatheter aortic valve replacement compared with White patients. Conclusions Hospitalization with any diagnosis of AS is less common in Black and Hispanic patients than in White patients. In hospitalized patients with AS, Black race is associated with a lower incidence of both surgical aortic valve replacement and transcatheter aortic valve replacement compared with White patients, whereas Hispanic patients have a similar incidence of both. The reasons for these inequities are likely multifactorial.
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Czarny et al. (2021) conducted an observational in Aortic stenosis. Black race vs. White race was evaluated on Surgical aortic valve replacement among those with any inpatient diagnosis of aortic stenosis (IRR 0.67, 95% CI 0.55-0.82, p=<0.001). Among hospitalized patients with aortic stenosis, Black race was associated with a significantly lower incidence of surgical aortic valve replacement compared with White race (IRR 0.67; 95% CI 0.55-0.82; P<0.001).
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