Key result
Axillary sheath magnesium sulphate 1.0% prolongs pain relief by ~172 minutes vs intramuscular diclofenac.
Why the study?
Does magnesium sulphate administered in the axillary sheath improve analgesia compared to intramuscular diclofenac in patients undergoing upper limb surgery?
Population
90 patients, age 20-60 years of either sex, ASA physical status I or II, scheduled for upper limb surgery.
Comparison
Magnesium sulphate given in axillary sheath just… vs Intramuscular diclofenac sodium 1 mg/kg.
Design
RCT, randomly allocated
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Supports perineural magnesium for extended analgesia after upper limb surgery; extends evidence for regional adjuncts versus systemic NSAIDs.
RCT (n=90)
randomly allocated
Does magnesium sulphate administered in the axillary sheath improve analgesia compared to intramuscular diclofenac in patients undergoing upper limb surgery?
Absolute Event Rate: 193.83% vs 21.66%
p-value: p=<.05
Magnesium sulphate administered independently in the axillary sheath provides effective analgesia and reduces morphine consumption after upper limb surgery compared to intramuscular diclofenac.
A 2009 study conducted an RCT in upper limb surgery (n=90). Magnesium sulphate vs. Intramuscular diclofenac sodium 1mg/kg was evaluated on Duration of pain relief (p=<.05). Magnesium sulphate 1.0% in the axillary sheath significantly prolonged pain relief duration (193.83 vs 21.66 minutes) compared to intramuscular diclofenac (p<.05).
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