Key result
Urinary N-acetyl-beta-D-glucosaminidase/creatinine ratio varies with age and helps detect pediatric renal tubular disease.
The urinary N-acetyl-beta-D-glucosaminidase/creatinine ratio varies with age in children and can be used to detect renal tubular disease.
Provides age-specific pediatric reference ranges for urinary NAG/creatinine; supports tubular disease detection but leaves open prospective validation.
The normal range for the urinary N-acetyl-beta-D-glucosaminidase/creatinine ratio was determined in 82 children. The range was found to vary with age, and the distribution was found to be logarithmic. This test should help to detect renal tubular disease in children; it gave abnormal results in some of these children.
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John Osborne (1980) studied this question. The normal range for the urinary N-acetyl-beta-D-glucosaminidase/creatinine ratio varies with age, follows a logarithmic distribution, and helps detect renal tubular disease in children.
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