Warming Up to Cold Perfusion

Each year, thousands of people in the United States die while awaiting lifesaving liver transplantation because there is an insufficient supply of donor organs. This crisis has prompted increased interest in expanding the organ supply through the promotion of both deceased and live liver donation and has led to the encouragement of use of organs from so-called expanded-criteria donation — grafts from older donors, grafts with suboptimal organ quality (e.g., with varying degrees of fatty liver deposits or steatosis), or grafts that had sustained prolonged ischemia times after they were obtained. Livers from deceased donors that are obtained after circulatory . . .