Key result
VSSR with De Paulis valsalva graft yields 90% freedom from reoperation at 5 years.
Why the study?
What are the early and midterm outcomes of the VSSR procedure with De Paulis valsalva graft in patients with acute aortic dissection or ascending aortic aneurysm?
Observational (n=38)
No
What are the early and midterm outcomes of the VSSR procedure with De Paulis valsalva graft in patients with acute aortic dissection or ascending aortic aneurysm?
The VSSR procedure with De Paulis valsalva graft demonstrates satisfactory early and midterm outcomes, including high rates of freedom from reoperation and valve replacement, in Chinese patients with aortic root pathology.
Adds observational support for VSSR with De Paulis graft; leaves open need for randomized confirmation of durability.
BACKGROUND: This study investigated early and midterm outcomes after valve-sparing aortic root replacement (VSSR procedure with De Paulis Valsalva graft) for acute aortic dissection or ascending aortic aneurysm in a single Chinese hospital center. METHODS: Between September 2005 to July 2013, 38 patients (84.2% male; mean age, 45.5 ± 12.4) underwent VSSR procedure with De Paulis valsalva graft for acute aortic dissection or ascending aortic aneurysm and were followed up clinically and echocardiographically. RESULTS: Among the 38 cases studied, intensive care unit stay duration was 34.5 (interquartile range, 16-34.6) days; hospital stay duration was 11.7 ± 7.9 days; operation time was 6.8 ± 1.9 h; and cross-clamping time was 154.4 ± 42.0 min. There was one intraoperative conversion to Bentall procedure; one re-operation for bleeding; one operative death and one case who developed complications. Mean follow-up was 39.7 ± 21.7 months (range, 12-108 months; cumulative rate, 1483 patients-months; follow-up rate, 94%). At 5 and 10 years, overall freedom from valve replacement was 94% and 87%; freedom from aortic regurgitation grade II or higher was 94% and 91%; and freedom from reoperation was 94% and 90% years, respectively. CONCLUSIONS: The reimplantation type of valve-sparing procedure appears to be facilitated by the use of the De Paulis valsalva graft with satisfactory perioperative and midterm results.
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Xu et al. (2015) conducted an observational in Acute aortic dissection or ascending aortic aneurysm (n=38). Valve-sparing aortic root replacement (VSSR) with De Paulis valsalva graft was evaluated on Freedom from reoperation at 5 years. The VSSR procedure with De Paulis valsalva graft yielded satisfactory midterm outcomes, with a 5-year freedom from reoperation of 90% and freedom from valve replacement of 87%.
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