In this study, amine-functionalized hollow mesoporous silica nanoparticles with an average diameter of ∼100 nm and shell thickness of ∼20 nm were prepared by an one-step process. This new nanoparticulate system exhibited excellent killing efficiency against mycobacterial (M. smegmatis strain mc(2) 651) and cancer cells (A549).
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Hao et al. (2015) studied this question.