Epidemiologic Study on Hepatitis A Virus Seroprevalence in Busan

The prevalence of hepatitis A virus (HAV) in a certain community reflects that community's living standard and hygienic condition.The seroprevalence rate of IgG anti-HAV has been changing with regions and times.In this study, we aimed to study the difference of seroprevalence of IgG anti-HAV according to sex, age and type of drinking water, and to know the vaccination rate and seroconversion rate for vaccinated subjects in Busan.A total of 644 samples were analyzed.The overall seroprevalence rate of IgG anti-HAV was 35.4% (228/644).There was no significant difference in sex (male 39.8%, female 32.7) (p＞0.05).According to age, seroprevalence rate of anti-HAV were 55.0% in subjects aged 5∼9 years old, 47.8% in 10∼14 years old, decreced to 10.6% in 15∼19 years old, 1.0% in 20∼24 years old, 0.0% in 25∼29 years old and increced with advacing ages ; 14.7% in 30∼34 years old, 39.4% in 35∼39 years old, 67.3% in 40∼44 years old, 94.1% in 45∼49 years old, 100.0%over 50 years (p＜0.001).The seroprevalence of IgG anti-HAV was no statistical difference according to the types of drinking water (p＞0.05).The vaccinated subject was 42 case only in below 25 years old.The seroconversion rate after vaccination was 88.1%.