BACKGROUND: leaf is not yet evaluated on changes of lipid profile in hepatic disease affected rats. OBJECTIVE: leaf and its isolated quercetin fraction on hepatotoxic rats. MATERIALS AND METHODS: ) was injected to rats for hepatic disease induction and silymarin drug was used as positive control to compare plant ethanolic extract. The lipid profiles were assessed in both plasma and liver tissue of diseased and control rats. RESULTS: (100, 200, and 300 mg/kg, bw) and isolated quercetin fraction (20 mg/kg, bw) doses decreased the elevated levels of all these parameters in diseased rats and restored the normal concentration of HDL-C. CONCLUSION: -induced hepatotoxic rats and decrease the disease rate. SUMMARY: : Carbon tetrachloride; FFA: Free fatty acids; HDL-C: High-density lipoprotein cholesterol; LCAT: Lecithin cholesterol acyltransferase; LDL-C: Low-density lipoprotein cholesterol; PL: Phospholipids; TC: Total cholesterol; TG: Triglycerides; VLDL-C: Very low-density lipoprotein cholesterol.
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Vijayakumar et al. (2018) studied this question.
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