Synthesis of 2′-deoxy-2′-α-monofluoromethyl and trifluoromethyl Nucleosides

All articles of this category Coupling of 2′-deoxy-2′-α-monofluoromethyl and trifluoromethyl ribose derivatives with bissilylated thymine afforded a mixture of α- and β- nucleosides which were further transformed into their corresponding pure β-phosphoramidites.