In this communication, we find that the single-walled carbon nanotubes (SWNTs) can demonstrate an excellent ssDNA concentration-dependent surface enhanced Raman scattering (SERS) effect after the decoration of DNA-templated in situ grown AgNPs on the surface. Inspired by this, the SWNT@AgNPs hybrid nanocomposite was employed to achieve microRNA detection which is also sensitive to crude extraction from human breast cancer cells and even patient tissues before and after chemotherapy.
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Zheng et al. (2015) studied this question.
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