Various 2,2-dimethyl-6-functional-2H-1-benzopyrans were prepared via a halogen-metal exchange reaction followed by treatment with electrophiles. These 6-functionalized chromenes are important synthetic intermediates for preparation of benzopyran-based potassium channel openers.
No takes yet. Share an insight, caveat, or question.
Charles Z. Ding (1996) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: