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Thermodynamic constants of the ionisation of the acid imino-group of uridine 5′-monophosphate (UMP-5′) and polyuridylic acid (poly-U) have been evaluated at various ionic strengths and temperatures by potentiometry. The low temperature titration of poly-U is consistent with the secondary structure probably being a double-helix.
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Nigel Aylward (1967) studied this question.
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