Key result
Review details the pathophysiology, comorbidities, and differential diagnosis of postcapillary PH in LHD.
Why the study?
Patients with postcapillary pulmonary hypertension associated with left heart diseases represent the most numerous cohort, yet remain not fully understood.
This review summarizes the pathophysiology and differential diagnosis of pulmonary hypertension due to left heart disease (Group 2 PH).
Differential diagnosis of postcapillary PH remains challenging; extends pathophysiological insights but leaves open prospective validation of combined forms.
The cohort of patients with postcapillary pulmonary hypertension (PH), associated with the left heart diseases, is the most numerous, but is still not fully understood. This review presents the pathophysiological aspects of the PH group 2 development as well as the influence of comorbid pathology on the course of the PH. The features of the differential diagnosis of post-capillary PH and combined post-/ precapillary PH, as well as methods of the differential diagnosis of these forms of PH with pulmonary arterial hypertension using modern non-invasive and invasive approaches are discussed.
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Lyapina et al. (2023) conducted a review in Pulmonary hypertension due to left heart disease. This review discusses the pathophysiology, influence of comorbidities, and differential diagnosis of postcapillary pulmonary hypertension associated with left heart disease.
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