Computational toxicology: a tool for all industries

Statistical, expert system, and machine learning methods among others have been used to developin silicotools for the prediction of toxicological hazard from chemical structure. The models are being applied to the mammalian and environmental toxicological assessment of chemicals across a range of industries including cosmetics, foods, industrial chemicals, and pharmaceuticals. Their use within a regulatory environment has also been encouraged by recent legislation. Generally, the models address the potential toxicity of low to medium molecular weight organic chemicals but models for other chemical types such as proteins and nanoparticles have also received some attention.